Open AccessHIV influences microtubule associated protein-2: potential marker of HIV-associated neurocognitive disorders
Author(s) -
Valeria Avdoshina,
Matthew Mahoney,
Sean F. Gilmore,
Erin D. Wenzel,
Albert M. Anderson,
Scott Letendre,
Tomozumi Imamichi,
Nicholas O. Fischer,
Italo Mocchetti
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002509
Subject(s) - neurotoxicity , microtubule , neurocognitive , dendrite (mathematics) , neuroscience , microtubule associated protein , biology , neuropathology , microbiology and biotechnology , medicine , pathology , toxicity , cognition , geometry , mathematics , disease
Postmortem brains of patients diagnosed with HIV-1-associated neurocognitive disorders (HAND) exhibit loss of dendrites. However, the mechanisms by which synapses are damaged are not fully understood.