Open AccessAssociations between recent thymic emigrants and CD4+ T-cell recovery after short-term antiretroviral therapy initiation
Author(s) -
Olivia Briceño,
Monserrat Chávez-Torres,
Amy Peralta-Prado,
Daniela Garrido-Rodríguez,
Karla Romero-Mora,
Sandra Pinto-Cardoso,
Gustavo ReyesTerán
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002458
Subject(s) - antiretroviral therapy , term (time) , medicine , immunology , human immunodeficiency virus (hiv) , sida , intensive care medicine , virology , viral disease , viral load , physics , quantum mechanics
Around 20-30% of HIV-infected individuals (HIV+) on successful antiretroviral therapy (ART) fail to normalize their CD4 T-cell counts. Various factors could contribute to the lack of immune reconstitution, one of them being thymic insufficiency. We aimed to explore associations between recent thymic emigrants (RTEs) and CD4 T-cell recovery.