Open AccessCognitive impairment severity in relation to signs of subclinical Wernicke's encephalopathy in HIV and alcoholism comorbidity
Author(s) -
AnnePascale Le Berre,
Rosemary Fama,
Stephanie A. Sassoon,
Natalie M. Zahr,
Adolf Pfefferbaum,
Edith V. Sullivan
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002428
Subject(s) - subclinical infection , comorbidity , encephalopathy , wernicke encephalopathy , wernicke's encephalopathy , medicine , neuropsychology , dementia , psychology , psychiatry , cognitive disorder , pediatrics , disease , cognition , thiamine , thiamine deficiency
The comorbidity of HIV infection and alcoholism (ALC) is prevalent. Wernicke's encephalopathy, a neurological disorder resulting from thiamine depletion, has been generally associated with alcoholism but has also been reported in HIV infection. This study examined whether subclinical Wernicke's encephalopathy signs could contribute to the heterogeneity of cognitive and motor deficits observed in individuals with both disease conditions (HIV+ALC).