Open AccessThe proportion of CD57+ cells among effector CD8+ T cells is lower in HIV controllers compared with antiretroviral therapy-treated patients
Author(s) -
Soledad Henriquez,
Camille Lécuroux,
Marie Bitu,
Véronique Avettand-Fènoël,
Françoise Churaqui,
P Catalán,
Antoine Chéret,
Faroudy Boufassa,
Asier SáezCirión,
Valérie Monceaux,
Laurence Meyer,
Cécile Goujard,
Olivier Lambotte,
Christine Bourgeois
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002342
Subject(s) - effector , antiretroviral therapy , cd8 , human immunodeficiency virus (hiv) , immunopathology , sida , immunology , lentivirus , cytotoxic t cell , viral disease , virology , medicine , viral load , biology , immune system , genetics , in vitro
HIV infection has often been linked to faster immune ageing. We sought to determine whether or not treatment-naive spontaneous HIV-1 controllers (HICs) and ART-exposed patients differ with regard to the expression of cell senescence markers.