Open AccessHIV-mediated immune aging in young adults infected perinatally or during childhood
Author(s) -
Solène Fastenackels,
Delphine Sauce,
Corinne Vigouroux,
Véronique Avettand-Fènoël,
JeanPhilippe Bastard,
Soraya Fellahi,
Laura Nailler,
Elisa Arezes,
Christine Rouzioux,
Josiane Warszawski,
Jean Paul Viard,
Victor Appay
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002275
Subject(s) - immunosenescence , immunology , immune system , young adult , medicine , senescence , viral load , premature aging , human immunodeficiency virus (hiv) , physiology
HIV-infected patients progressing towards disease present a premature immune aging profile, characterized by the exhaustion of lymphopoiesis. The development of these anomalies may be prevented in young HIV-infected patients owing to their robust immune resources and lymphocyte regeneration capacities.