Open AccessThe anti-inflammatory IL-37/SIGIRR axis is functionally compromised in HIV infection
Author(s) -
Suzanne Samarani,
Ayoub Abulkhir,
Devendra Amre,
Vikram Mehraj,
Cécile Tremblay,
JeanPierre Routy,
Ali Ahmad
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002271
Subject(s) - human immunodeficiency virus (hiv) , immunology , medicine , inflammation
IL-37 is a member of the IL-1 family with potent anti-inflammatory effects. Little is known about regulation of the cytokine and of its signaling co-receptor SIGIRR in HIV infection.