Open AccessTenofovir concentrations in hair strongly predict virologic suppression in breastfeeding women
Author(s) -
Pamela M. Murnane,
Peter Bacchetti,
Judith S. Currier,
Sean Brummel,
Hideaki Okochi,
Nhi Phung,
Alan K. Louie,
Karen Kuncze,
Risa M. Hoffman,
Teacler Nematadzira,
Dean Soko,
Maxensia Owor,
Friday Saidi,
Patricia M. Flynn,
Mary Glenn Fowler,
Monica Gandhi
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002237
Subject(s) - medicine , breastfeeding , interquartile range , odds ratio , confidence interval , viral load , generalized estimating equation , breast feeding , postpartum period , viremia , geometric mean , obstetrics , pregnancy , human immunodeficiency virus (hiv) , immunology , pediatrics , biology , statistics , mathematics , genetics
Antiretroviral treatment (ART) adherence is often suboptimal in the perinatal period. We measured hair tenofovir (TFV) concentrations as a metric of adherence in postpartum women to understand patterns and predictors of adherence throughout this critical period. In addition, we examined the association between hair TFV concentrations and virologic outcomes.