Open AccessHIV infection and cerebral small vessel disease are independently associated with brain atrophy and cognitive impairment
Author(s) -
Ryan Sanford,
Jeremy F. Strain,
Mahsa Dadar,
Josefina Maranzano,
Alexandre Bonnet,
Nancy E. Mayo,
Susan C. Scott,
Lesley K. Fellows,
Beau M. Ances,
D. Louis Collins
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002193
Subject(s) - neuropsychology , hyperintensity , atrophy , cognition , serostatus , brain size , cerebral atrophy , medicine , psychology , lateralization of brain function , effects of sleep deprivation on cognitive performance , boston naming test , audiology , human immunodeficiency virus (hiv) , neuroscience , magnetic resonance imaging , viral load , immunology , radiology
The objective of this study is to investigate whether cerebral small vessel disease (CSVD) is more common in virologically suppressed HIV-positive participants compared with HIV-negative controls and examine the potential synergistic effects of HIV and CSVD on brain structure and cognition.