Open AccessDoes bacterial vaginosis modify the effect of hormonal contraception on HIV seroconversion
Author(s) -
Michelle C Sabo,
Barbra A. Richardson,
Ludo Lavreys,
Harold L. Martin,
Walter Jaoko,
Kishorchandra Mandaliya,
Jared M. Baeten,
Julie Overbaugh,
R. Scott McClelland
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002167
Subject(s) - bacterial vaginosis , medicine , medroxyprogesterone acetate , seroconversion , gynecology , obstetrics , population , hormonal contraception , prospective cohort study , serodiscordant , medroxyprogesterone , confidence interval , cohort study , human immunodeficiency virus (hiv) , estrogen , family planning , immunology , viral load , antiretroviral therapy , environmental health , research methodology
A recent study of HIV serodiscordant couples found that depot medroxyprogesterone acetate (DMPA) and oral contraceptive pills (OCPs) were associated with increased HIV risk in the presence, but not in the absence, of bacterial vaginosis. We assessed whether bacterial vaginosis is an effect modifier of the association between hormonal contraception and HIV seroconversion in female sex workers (FSWs) in Mombasa, Kenya.