Open AccessDistinct gut microbiota profile in antiretroviral therapy-treated perinatally HIV-infected patients associated with cardiac and inflammatory biomarkers
Author(s) -
Libera Sessa,
Sofia Reddel,
Emma Concetta Manno,
Andrea Quagliariello,
Nicola Cotugno,
Federica Del Chierico,
Donato Amodio,
Claudia Capponi,
F. Leone,
Stefania Bernardi,
Paolo Rossi,
Lorenza Putignani,
Paolo Palma
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002131
Subject(s) - antiretroviral therapy , gut flora , human immunodeficiency virus (hiv) , medicine , immunology , sida , viral load , virology , viral disease
Persistent inflammation and higher risk to develop cardiovascular diseases still represent a major complication for HIV-infected patients despite effective antiretroviral therapy (ART). We investigated the correlation between the gut microbiota profile, markers of inflammation, vascular endothelial activation (VEA) and microbial translocation (MT) in perinatally HIV-infected patients (PHIV) under ART.