Open AccessIncreased risk of anal squamous cell carcinoma in HIV-positive men with prior hepatitis B virus infection
Author(s) -
Jordan Aldersley,
David R. Lorenz,
Vikas Misra,
Hajime Uno,
Dana Gabuzda
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002059
Subject(s) - medicine , anal cancer , multicenter aids cohort study , hepatitis b virus , rate ratio , confidence interval , prospective cohort study , gastroenterology , risk factor , immunology , cancer , viral disease , sida , virus
HIV-positive individuals have elevated rates of anal squamous cell carcinoma (SCC), and sexually transmitted infections with its causative agent, high-risk human papillomavirus, and other oncoviruses including hepatitis B virus (HBV). HBV infection can cause liver cancer, and has been associated with increased risk of some extra-hepatic cancers including biliary tract cancer, pancreatic cancer, and non-Hodgkin lymphoma. Whether HBV is associated with anal SCC risk is unknown.