Open AccessAtrophic brain signatures of mild forms of neurocognitive impairment in virally suppressed HIV infection
Author(s) -
Madeleine J. Nichols,
Thomas M. Gates,
James Soares,
Kirsten Moffat,
Caroline Rae,
Bruce J. Brew,
Lucette A Cysique
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002042
Subject(s) - neurocognitive , white matter , atrophy , grey matter , hyperintensity , medicine , asymptomatic , dementia , magnetic resonance imaging , neuropsychology , pathology , psychiatry , radiology , disease , cognition
There is a lack of evidence for the neurobiological underpinning of asymptomatic neurocognitive impairment (ANI) and mild neurocognitive disorders (MNDs) in virally suppressed HIV-positive persons. We hypothesized that such mild impairment would be associated with focal brain atrophy.