Open AccessViremia copy-years and mortality among combination antiretroviral therapy-initiating HIV-positive individuals
Author(s) -
Ruibin Wang,
Sabina A. Haberlen,
Frank J. Palella,
Michael J. Mugavero,
Joseph B. Margolick,
Bernard Macatangay,
Otoniel Martı́nez-Maza,
Lisa P. Jacobson,
Alison G. Abraham
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001986
Subject(s) - cart , viral load , viremia , medicine , immunology , cohort , virology , human immunodeficiency virus (hiv) , mechanical engineering , engineering
Ongoing HIV replication while receiving combination antiretroviral therapy (cART) may reduce survival. Viremia copy-years (VCY) has shown improved mortality risk prediction over single time-point viral load measures. However, the timing of a patient's viral load history most associated with later mortality has not been studied. Here we determined the optimal duration and temporality of viral load history for predicting mortality.