Open AccessRapid CD4+ T-cell decline is associated with coreceptor switch among MSM primarily infected with HIV-1 CRF01_AE in Northeast China
Author(s) -
Hu Cui,
Wenqing Geng,
Hong Sun,
Xiaoxu Han,
Minghui An,
Yongjun Jiang,
Zining Zhang,
Zhiwei Chen,
Junjie Xu,
Qinghai Hu,
Bin Zhao,
Bennan Zhou
Publication year - 2019
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001981
Subject(s) - virology , china , human immunodeficiency virus (hiv) , lentivirus , sida , men who have sex with men , biology , viral disease , medicine , geography , syphilis , archaeology
CRF01_AE is the most prevalent HIV-1 subtype among MSM in China. However, the characteristics and underlying mechanism of the accelerated CD4 T-cell decline in CRF01_AE-infected MSM remain incompletely understood.