Open AccessClinical research cerebral MRI findings in HIV-positive subjects and appropriate controls
Author(s) -
Srishti Chhabra,
Jonathan Underwood,
James H. Cole,
Matthan W.A. Caan,
Adam Waldman,
Peter Reiss,
Caroline Sabin,
David J. Sharp,
Alan Winston
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001910
Subject(s) - medicine , serostatus , magnetic resonance imaging , human immunodeficiency virus (hiv) , white matter , cardiology , pathology , pediatrics , radiology , immunology , viral load
: Abnormalities in cerebral MRI are frequently reported in persons living with HIV (PLWH). We compared clinical cerebral MRI reports in 59 PLWH and 29 lifestyle matched controls. Although clinical abnormalities were highly prevalent (47.7%), and included white-matter lesions (46.6%), microvascular disease (22.7%) and cerebral volume loss (11.4%), no differences were apparent between PLWH and controls, with abnormalities being associated with age and hypertension rather than HIV serostatus.