Open AccessMultimorbidity, age-related comorbidities and mortality
Author(s) -
Pierre Duffau,
Alexandra Ozanne,
Fabrice Bonnet,
Estibaliz Lazaro,
Charles Cazanave,
Patrick Blanco,
Étienne Rivière,
A. Desclaux,
Caroline Hyernard,
Noémie Gensous,
Isabelle Pellegrin,
Linda Wittkop
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001875
Subject(s) - comorbidity , multimorbidity , medicine , gerontology , intensive care medicine
The widespread introduction of combination antiretroviral therapy (cART) has increased survival of HIV-infected patients. However, the prevalence of age-related comorbidities remains higher than that of the general population, suggesting that individuals with HIV suffer from accelerated aging. Immune activation, senescence and inflammation could play an important role in this process.