Open AccessIncreased cholesterol absorption rather than synthesis is involved in boosted protease inhibitor-associated hypercholesterolaemia
Author(s) -
Pere Leyes,
Montserrat Cofán,
Ana González-Cordón,
Elisa de Lazzari,
Joan Trabal,
Peré Domingo,
Eugènia Negredo,
Francesc Vidal,
María Forga,
José M. Gatell,
Emili Ros,
Estebán Martínez
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001837
Subject(s) - lopinavir , ritonavir , cholesterol , lathosterol , efavirenz , triglyceride , pharmacology , medicine , apolipoprotein b , campesterol , emtricitabine , gastroenterology , endocrinology , human immunodeficiency virus (hiv) , sterol , antiretroviral therapy , viral load , virology
The aim of this study was to compare the differential effects of first-line efavirenz (EFV)-based vs. boosted lopinavir-based antiretroviral regimens on cholesterol metabolism.