Open AccessEffects of HIV, antiretroviral therapy and prebiotics on the active fraction of the gut microbiota
Author(s) -
Simon Deusch,
Sergio SerranoVillar,
David Rojo,
Mónica Martínez-Martínez,
Rafael Bargiela,
Jorge F. Vázquez-Castellanos,
Talía Sainz,
Coral Barbas,
Andrés Moyá,
Santiago Moreno,
María José Gosalbes,
Vicente Estrada,
Jana Seifert,
Manuel Ferrer
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001831
Subject(s) - dysbiosis , prebiotic , gut flora , immunology , biology , medicine , genetics
In a recent blinded randomized study, we found that in HIV-infected individuals a short supplementation with prebiotics (scGOS/lcFOS/glutamine) ameliorates dysbiosis of total gut bacteria, particularly among viremic untreated patients. Our study goal was to determine the fraction of the microbiota that becomes active during the intervention and that could provide additional functional information.