Open AccessDetection of numerous HIV-1/MO recombinants in France
Author(s) -
Fabienne De Oliveira,
Pierre Cappy,
Veronique Lemée,
Alice Moisan,
Charlotte Pronier,
Laurence Bocket,
Magali BouvierAlias,
MarieLaure Chaix,
Elyanne Gault,
Odile Morvan,
Jean-Dominique Poveda,
Véronique Schneider,
Marc Wirden,
Elodie Alessandri-Gradt,
Thomas Mourez,
JeanChristophe Plantier
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001814
Subject(s) - recombinant dna , serology , human immunodeficiency virus (hiv) , virology , medicine , virus , biology , immunology , antibody , genetics , gene
The broad genetic divergence of HIV-1/O relative to HIV-1/M has important implications for diagnosis, monitoring and treatment. Despite this divergence, some HIV-1/M+O dual infections and HIV-1/MO recombinant forms have been reported, mostly in Cameroon, where both groups are prevalent. Here, we describe the characteristics of such infections detected in France in 10 new patients, and discuss their implications for biological and clinical practice, owing to the presence of group O species.