Open AccessTMC120 displayed potent cytotoxic effect on human cervical carcinoma through enhancing the polymerization of microtubules
Author(s) -
Lili Shi,
Li Yu,
Desheng Zhong,
Congwei Gu,
Longyun Lv,
Xianmin Zeng,
Xingang Yao,
Lin Li,
Shuwen Liu
Publication year - 2018
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000001808
Subject(s) - hela , in vivo , cytotoxic t cell , medicine , cancer , cancer research , paclitaxel , mtt assay , cervical cancer , cell cycle , apoptosis , pharmacology , immunology , cell culture , in vitro , biology , biochemistry , genetics , microbiology and biotechnology
In the post-HAART era, the incidence of some AIDS-defining cancers declined markedly likely reflecting HAART-related improvements in immunity, whereas incidence of some cancers such as cervical cancer has not been affected. Therefore, it is valuable to find whether antiretroviral drugs or prophylactic microbicides could treat or prevent these cancers, especially the cervical cancer.