Open AccessDecreasing cardiovascular risk in HIV infection between 2005 and 2011
Author(s) -
Giuseppe Vittorio De Socio,
Giustino Parruti,
Elena Ricci,
Paolo Maggi,
Benedetto Maurizio Celesia,
Giovanni Penco,
Canio Martinelli,
Marco Franzetti,
Antonio Di Biagio,
Paolo Bonfanti,
Giacomo Pucci,
Giuseppe Schillaci
Publication year - 2014
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000000181
Subject(s) - medicine , framingham risk score , lipodystrophy , human immunodeficiency virus (hiv) , metabolic syndrome , obesity , disease , immunology , viral load , antiretroviral therapy
Cardiovascular risk profile was compared in 765 Italian HIV-infected outpatients enrolled in 2005 and in 765 individually age-matched and sex-matched patients enrolled in 2011. Median Framingham risk score was 8.6% in 2005 vs. 7.9% in 2011 (P = 0.04); metabolic syndrome was present in 40.3% vs. 33.4% (P = 0.006). Blood glucose, triglycerides, prevalence of smokers, and lipodystrophy were all significantly lower in 2011 (all P < 0.0001). Cardiovascular risk improved over a 6-year period in Italian HIV-infected patients.