Open AccessNot Seeing Double: Discordance in Disease, Function, and Their Longitudinal Associations in Monozygotic Twins
Author(s) -
Elizabeth Teas,
Olivia Robertson,
Kristine Marceau,
Elliot Friedman
Publication year - 2021
Publication title -
psychosomatic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.62
H-Index - 187
eISSN - 1534-7796
pISSN - 0033-3174
DOI - 10.1097/psy.0000000000000972
Subject(s) - moderation , twin study , disease , psychology , monozygotic twin , association (psychology) , functional impairment , developmental psychology , longitudinal study , clinical psychology , medicine , heritability , biology , genetics , pathology , social psychology , psychotherapist
Prior research on the causality and directionality between disease and functional limitations is ambiguous. The current study used longitudinal monozygotic twin data to test both directions linking disease burden and functional limitations in middle-aged and older adults, controlling for genetic and familial factors. We also examined potential moderation by psychological well-being.