Open AccessGenetic Overlap Between Type 2 Diabetes and Depression in a Sri Lankan Population Twin Sample
Author(s) -
Carol Kan,
Kaushalya Jayaweera,
Anushka Adikari,
Sisira Siribaddana,
Helena M. S. Zavos,
Lisa Harber-Aschan,
Athula Sumathipala,
Matthew Hotopf,
Khalida Ismail,
Frühling Rijsdijk
Publication year - 2019
Publication title -
psychosomatic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.62
H-Index - 187
eISSN - 1534-7796
pISSN - 0033-3174
DOI - 10.1097/psy.0000000000000771
Subject(s) - twin study , genetic correlation , type 2 diabetes , dizygotic twin , context (archaeology) , depression (economics) , correlation , population , bivariate analysis , beck depression inventory , diabetes mellitus , medicine , demography , heritability , genetic variation , genetics , biology , psychiatry , statistics , endocrinology , environmental health , economics , macroeconomics , mathematics , anxiety , sociology , paleontology , geometry
Results from twin studies examining the genetic overlap between type 2 diabetes and depression are currently inconclusive. This question has not been addressed in non-Western populations. We aimed to examine whether there are common genetic factors between type 2 diabetes and depression in a Sri Lankan population using genetic model-fitting analysis.