Open AccessDiffusion Magnetic Resonance Imaging Predicts Peripheral Nerve Recovery in a Rat Sciatic Nerve Injury Model
Author(s) -
Ángel Fariñas,
Isaac V. Manzanera Esteve,
Alonda C. Pollins,
Nancy L. Cardwell,
Christodoulos Kaoutzanis,
Marlieke E. Nussenbaum,
Mark D. Does,
Richard D. Dortch,
Galen Perdikis,
Wesley P. Thayer
Publication year - 2020
Publication title -
plastic and reconstructive surgery/psef cd journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.841
H-Index - 179
eISSN - 1076-5751
pISSN - 0032-1052
DOI - 10.1097/prs.0000000000006638
Subject(s) - medicine , sciatic nerve , fractional anisotropy , magnetic resonance imaging , diffusion mri , reinnervation , tractography , nerve injury , crush injury , regeneration (biology) , anatomy , anesthesia , surgery , radiology , biology , microbiology and biotechnology
Nerve regeneration after an injury should occur in a timely fashion for function to be restored. Current methods cannot monitor regeneration prior to muscle reinnervation. Diffusion tensor imaging has been previously shown to provide quantitative indices after nerve recovery. The goal of this study was to validate the use of this technology following nerve injury via a series of rat sciatic nerve injury/repair studies.