
Rheologic and Physicochemical Properties Used to Differentiate Injectable Hyaluronic Acid Filler Products
Author(s) -
Steven Fagien,
Vince Bertucci,
Erika von Grote,
Jay Mashburn
Publication year - 2019
Publication title -
plastic and reconstructive surgery/psef cd journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.841
H-Index - 179
eISSN - 1076-5751
pISSN - 0032-1052
DOI - 10.1097/prs.0000000000005429
Subject(s) - swelling , hyaluronic acid , rheology , cohesion (chemistry) , materials science , biomedical engineering , composite material , chemistry , medicine , organic chemistry , anatomy
Injectable hyaluronic acid fillers are routinely used for correction of soft-tissue volume loss and facial rejuvenation. Product differentiation has primarily been based on the rheologic parameter known as elastic modulus (G'), although other physicochemical properties are being explored to characterize potential product performance. As clinical data regarding product performance are lacking, the practical experience of injectors provides a valuable bridge in the knowledge gap between product rheologic data and product use.