
Noninvasive vagus nerve stimulation and morphine transiently inhibit trigeminal pain signaling in a chronic headache model
Author(s) -
Lauren E. Cornelison,
Jordan Hawkins,
Sara Woodman,
Paul L. Durham
Publication year - 2020
Publication title -
pain reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 15
ISSN - 2471-2531
DOI - 10.1097/pr9.0000000000000881
Subject(s) - medicine , nociception , migraine , anesthesia , trigeminal nerve , sensitization , vagus nerve , chronic pain , morphine , pharmacology , serotonergic , stimulation , receptor , serotonin , psychiatry , immunology
Noninvasive vagus nerve stimulation suppressed persistent trigeminal nociception in a chronic headache model similarly to morphine and may provide a safe, nonaddictive abortive therapy for chronic headache.