
Changes in blood–spinal cord barrier permeability and neuroimmune interactions in the underlying mechanisms of chronic pain
Author(s) -
Karli Montague-Cardoso,
Marzia Malcangio
Publication year - 2021
Publication title -
pain reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 15
ISSN - 2471-2531
DOI - 10.1097/pr9.0000000000000879
Subject(s) - spinal cord , neuroscience , chronic pain , medicine , microglia , immune system , neuropathic pain , crosstalk , immunology , inflammation , psychology , physics , optics
Here, we discuss evidence for changes in blood–spinal cord barrier permeability and consider the possibility of associated neuroimmune communication changes in models of chronic pain.