Open AccessRegular physical activity reduces the percentage of spinally projecting neurons that express mu-opioid receptors from the rostral ventromedial medulla in mice
Author(s) -
Kathleen A. Sluka,
Jessica Danielson,
Lynn Rasmussen,
Sandra J. Kolker
Publication year - 2020
Publication title -
pain reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 15
ISSN - 2471-2531
DOI - 10.1097/pr9.0000000000000857
Subject(s) - rostral ventromedial medulla , medulla , opioid , neuroscience , receptor , chemistry , psychology , nociception , biology , medicine , anatomy , hyperalgesia
Physically active animals have less mu-opioid-expressing neurons projecting to the spinal cord in the rostral ventromedial medulla, but not the nucleus raphe obscurus/nucleus raphe pallidus, when compared to sedentary animals.