Open AccessA new role of growth hormone and insulin growth factor receptor type 1 in neonatal inflammatory nociception
Author(s) -
Alfredo ManzanoGarcía,
Mohammed Gamal-Eltrabily
Publication year - 2017
Publication title -
pain reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 15
ISSN - 2471-2531
DOI - 10.1097/pr9.0000000000000608
Subject(s) - nociception , insulin like growth factor , growth factor , receptor , inflammation , endocrinology , sensitization , medicine , growth hormone , carrageenan , peripheral , insulin , hormone , pharmacology , immunology
Neonatal inflammation produces nociception by a local decrease of growth hormone and an increment of the insulin growth factor 1-1R. Systemic growth hormone prevents the development of nociception.