Open AccessMethylphenidate attenuates the response to cold pain but not to aversive auditory stimuli in healthy human: a double-blind randomized controlled study
Author(s) -
Dorit Pud,
Eelena Broitman,
Omar Hameed,
Erica Suzan,
Joshua Aviram,
May Haddad,
Salim Hadad,
Rafi Shemesh,
Elon Eisenberg
Publication year - 2017
Publication title -
pain reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.113
H-Index - 15
ISSN - 2471-2531
DOI - 10.1097/pr9.0000000000000593
Subject(s) - crossover study , pain tolerance , placebo , methylphenidate , anesthesia , nociception , threshold of pain , audiology , medicine , stimulation , psychology , cold pressor test , aversive stimulus , attention deficit hyperactivity disorder , heart rate , developmental psychology , psychiatry , alternative medicine , receptor , pathology , blood pressure
This double-blind, crossover, randomized placebo-controlled study found that methylphenidate has a specific effect on nociceptive pathways rather than a generalized effect on aversive sensory modalities.