Open AccessEndocervical Adenocarcinoma, Gross Examination, and Processing, Including Intraoperative Evaluation: Recommendations From the International Society of Gynecological Pathologists
Author(s) -
Carlos ParraHerran,
Anaís Malpica,
Esther Oliva,
Gian Franco Zani,
Pedro T. Ramírez,
Joseph T. Rabban
Publication year - 2021
Publication title -
international journal of gynecological pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 77
eISSN - 1538-7151
pISSN - 0277-1691
DOI - 10.1097/pgp.0000000000000745
Subject(s) - trachelectomy , medicine , cervical cancer , gross examination , adenocarcinoma , hysterectomy , general surgery , radiology , gynecology , cancer , pathology
The International Society of Gynecological Pathologists (ISGyP) Endocervical Adenocarcinoma Project aims to provide evidence-based guidance for the pathologic evaluation, classification, and reporting of endocervical adenocarcinoma. This review presents the recommendations pertaining to gross evaluation and intraoperative consultation of specimens obtained from patients in the setting of cervical cancer. The recommendations are the product of review of published peer-reviewed evidence, international guidelines and institutional grossing manuals, as well as deliberation within this working group. The discussion presented herein details the approach to the different specimen types encountered in practice: loop electrosurgical excision procedure, cone, trachelectomy, radical hysterectomy, pelvic exenteration, and lymphadenectomy specimens. Guidelines for intraoperative evaluation of trachelectomy and sentinel lymph node specimens are also addressed. Correlation with ISGyP recommendations on cancer staging, which appear as a separate review in this issue, is also included when appropriate. While conceived in the framework of endocervical adenocarcinoma, most of the discussion and recommendations can also be applied to other cervical malignancies.