Open AccessEndometrial Carcinoma, Grossing and Processing Issues: Recommendations of the International Society of Gynecologic Pathologists
Author(s) -
Anaís Malpica,
Elizabeth D. Euscher,
Jonathan L. Hecht,
Rouba Ali-Fehmi,
Charles M. Quick,
Naveena Singh,
Lars Christian Horn,
Isabel AlvaradoCabrero,
Xavier MatíasGuiu,
Lynn Hirschowitz,
Máire A. Duggan,
Jaume Ordï,
Vinita Parkash,
Yoshiki Mikami,
M. Ruhul Quddus,
Richard J. Zaino,
Annette Staebler,
Charles Zaloudek,
W. Glenn McCluggage,
Esther Oliva
Publication year - 2019
Publication title -
international journal of gynecological pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.925
H-Index - 77
eISSN - 1538-7151
pISSN - 0277-1691
DOI - 10.1097/pgp.0000000000000552
Subject(s) - medicine , endometrial cancer , hysterectomy , gynecologic cancer , dissection (medical) , general surgery , carcinoma , lymph node , gynecology , gross examination , cancer , radiology , pathology , ovarian cancer
Endometrial cancer is the most common gynecologic neoplasm in developed countries; however, updated universal guidelines are currently not available to handle specimens obtained during the surgical treatment of patients affected by this disease. This article presents recommendations on how to gross and submit sections for microscopic examination of hysterectomy specimens and other tissues removed during the surgical management of endometrial cancer such as salpingo-oophorectomy, omentectomy, and lymph node dissection-including sentinel lymph nodes. In addition, the intraoperative assessment of some of these specimens is addressed. These recommendations are based on a review of the literature, grossing manuals from various institutions, and a collaborative effort by a subgroup of the Endometrial Cancer Task Force of the International Society of Gynecological Pathologists. The aim of these recommendations is to standardize the processing of endometrial cancer specimens which is vital for adequate pathological reporting and will ultimately improve our understanding of this disease.