Open AccessUpper Gastrointestinal Bleeding as the First Presentation of Eosinophilic Gastrointestinal Disease
Author(s) -
Ozdogan Elif,
Caglayan Latife Doganay,
Mizikoglu Ozlem,
Arikan Cigdem
Publication year - 2020
Publication title -
jpgn reports
Language(s) - English
Resource type - Journals
ISSN - 2691-171X
DOI - 10.1097/pg9.0000000000000017
Subject(s) - medicine , eosinophilia , gastrointestinal disease , gastrointestinal bleeding , presentation (obstetrics) , disease , eosinophilic , upper gastrointestinal bleeding , gastrointestinal system , dermatology , gastroenterology , pediatrics , intensive care medicine , surgery , pathology , endoscopy
Gastrointestinal bleeding is a rare but potentially life‐threatening manifestation of eosinophilic gastrointestinal disorders (EGIDs). Here, we describe a case series comprising 5 pediatric patients between 7 and 12 years of age, who presented to the emergency department with hematemesis and were subsequently diagnosed with EGID. Accompanying allergic history, peripheral eosinophilia, and total IgE elevation were common. Despite a more severe presentation, response to medical and dietary therapy was favorable. A comprehensive review of the literature revealed 26 other cases with similar findings that reinforced the importance of prompt recognition and early dietary and immunomodulating therapy in the control of this disease.