Open AccessIntracranial and Cerebral Perfusion Pressure Thresholds Associated With Inhospital Mortality Across Pediatric Neurocritical Care*
Author(s) -
Kendra Woods,
Christopher M. Horvat,
Sajel Kantawala,
Dennis Simon,
Jaskaran Rakkar,
Patrick M. Kochanek,
Robert S. B. Clark,
Alicia K. Au
Publication year - 2020
Publication title -
pediatric critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.299
H-Index - 87
eISSN - 1947-3893
pISSN - 1529-7535
DOI - 10.1097/pcc.0000000000002618
Subject(s) - cerebral perfusion pressure , medicine , neurointensive care , intracranial pressure , traumatic brain injury , anesthesia , pediatric intensive care unit , intracranial pressure monitoring , intensive care , cerebral blood flow , pediatrics , intensive care medicine , psychiatry
Targets for treatment of raised intracranial pressure or decreased cerebral perfusion pressure in pediatric neurocritical care are not well defined. Current pediatric guidelines, based on traumatic brain injury, suggest an intracranial pressure target of less than 20 mm Hg and cerebral perfusion pressure minimum of 40-50 mm Hg, with possible age dependence of cerebral perfusion pressure. We sought to define intracranial pressure and cerebral perfusion pressure thresholds associated with inhospital mortality across a large single-center pediatric neurocritical care cohort.