Open AccessBiomarkers for Estimating Risk of Hospital Mortality and Long-Term Quality-of-Life Morbidity After Surviving Pediatric Septic Shock: A Secondary Analysis of the Life After Pediatric Sepsis Evaluation Investigation*
Author(s) -
Hector R. Wong,
Ron Reeder,
Russell Banks,
Robert A. Berg,
Kathleen L. Meert,
Mark W. Hall,
Patrick S. McQuillen,
Peter M. Mourani,
Ranjit S. Chima,
Samuel Sorenson,
James W. Varni,
Julie McGalliard,
Jerry J. Zimmerman
Publication year - 2020
Publication title -
pediatric critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.299
H-Index - 87
eISSN - 1947-3893
pISSN - 1529-7535
DOI - 10.1097/pcc.0000000000002572
Subject(s) - medicine , sepsis , septic shock , odds ratio , biomarker , risk of mortality , intensive care medicine , emergency medicine , pediatrics , biochemistry , chemistry
The Life After Pediatric Sepsis Evaluation investigation recently reported that one-third of children who survive sepsis experience significant health-related quality-of-life impairment compared with baseline at 1 year after hospitalization. Pediatric Sepsis Biomarker Risk Model is a multibiomarker tool for estimating baseline risk of mortality among children with septic shock. We determined if the Pediatric Sepsis Biomarker Risk Model biomarkers have predictive capacity for estimating the risk of hospital mortality and long-term health-related quality-of-life morbidity among children with community-acquired septic shock.