Open AccessHigh Expression of Yes-activated Protein-1 in Papillary Thyroid Carcinoma Correlates With Poor Prognosis
Author(s) -
Zeming Liu,
Wen Zeng,
Yusufu Maimaiti,
Jie Ming,
Yinglu Guo,
Yan Liu,
Chunping Liu,
Tao Huang
Publication year - 2019
Publication title -
applied immunohistochemistry and molecular morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.868
H-Index - 60
eISSN - 1541-2016
pISSN - 1533-4058
DOI - 10.1097/pai.0000000000000544
Subject(s) - medicine , immunohistochemistry , univariate analysis , thyroid carcinoma , oncology , pathology , context (archaeology) , lymph node , thyroid , cancer research , multivariate analysis , biology , paleontology
The Hippo signal transduction pathway is highly conserved in mammals. It plays a critical role in tissue and organ size by regulating the balance between cell proliferation and apoptosis. However, there have been few reports concerning Yes-activated protein-1 (YAP-1) elevation in papillary thyroid cancer (PTC).