Open AccessThe Rapid Plasma Reagin Test Cannot Replace the Venereal Disease Research Laboratory Test for Neurosyphilis Diagnosis
Author(s) -
Christina M. Marra,
Lauren C. Tantalo,
Clare Maxwell,
Emily Ho,
Sharon K. Sahi,
Timothy A. Jones
Publication year - 2012
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0b013e31824b1cde
Subject(s) - rapid plasma reagin , neurosyphilis , medicine , syphilis , cerebrospinal fluid , titer , gastroenterology , syphilis serodiagnosis , treponema , immunology , antibody , human immunodeficiency virus (hiv)
The cerebrospinal fluid (CSF) Venereal Disease Research Laboratory (VDRL) test is a mainstay for neurosyphilis diagnosis, but it lacks diagnostic sensitivity and is logistically complicated. The rapid plasma reagin (RPR) test is easier to perform, but its appropriateness for use on CSF is controversial.