Open AccessLimitations of the Dye-Based Method for Determining Vaginal Applicator Use in Microbicide Trials
Author(s) -
Michele N. Austin,
Lorna Rabe,
Sharon L. Hillier
Publication year - 2009
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0b013e3181972397
Subject(s) - microbicide , medicine , intravaginal administration , stain , gram staining , vagina , microbicides for sexually transmitted diseases , staining , polypropylene , surgery , biomedical engineering , population , pathology , antibiotics , microbiology and biotechnology , materials science , virology , composite material , biology , environmental health , human immunodeficiency virus (hiv) , health services
A dye-based method for determining applicator usage in microbicide trials has been developed to assess whether applicators have been exposed to vaginal fluid. Our objective was to evaluate this method on polypropylene HTI applicators that are being widely used in several effectiveness trials of microbicides.