Open AccessA Comparison of Treponema pallidum Subspecies pallidum Molecular Typing Systems: Multilocus Sequence Typing vs. Enhanced Centers for Disease Control and Prevention Typing
Author(s) -
Sharon K. Sahi,
Jana M Zahlan,
Lauren C. Tantalo,
Christina M. Marra
Publication year - 2021
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000001378
Subject(s) - multilocus sequence typing , typing , treponema , syphilis , sexually transmitted disease , medicine , neurosyphilis , subspecies , biology , virology , pathology , genetics , microbiology and biotechnology , genotype , gene , zoology , human immunodeficiency virus (hiv)
At least 3 syphilis typing systems are proposed. Recent work suggests that multilocus sequence typing (MLST) may be superior to enhanced Centers for Disease Control and Prevention typing (ECDCT) by yielding a higher discriminatory power. The goal of this study was to compare the 2 systems and identify associations between neurosyphilis and strain types.