Open AccessVaginal Bacteria and Risk of Incident and Persistent Infection With High-Risk Subtypes of Human Papillomavirus: A Cohort Study Among Kenyan Women
Author(s) -
Kayla A. Carter,
Sujatha Srinivasan,
Tina L. Fiedler,
Omu Anzala,
Joshua Kimani,
Ver Mochache,
Jacqueline M Wallis,
David N. Fredricks,
R. Scott McClelland,
Jennifer E. Balkus
Publication year - 2020
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000001343
Subject(s) - lactobacillus crispatus , bacterial vaginosis , medicine , odds ratio , prospective cohort study , vaginal flora , confidence interval , gynecology , vagina , incidence (geometry) , cohort study , obstetrics , lactobacillus , biology , bacteria , surgery , genetics , physics , optics
Bacterial vaginosis (BV) is associated with an increased risk of high-risk human papillomavirus (hrHPV), whereas Lactobacillus-dominated vaginal microbiotas are associated with reduced burden of hrHPV. Few epidemiologic studies have prospectively investigated the relationships between vaginal bacteria and hrHPV, particularly among women from countries in Africa.