Open AccessA Dual-Platform Point-of-Care Test for Neurosyphilis Diagnosis
Author(s) -
Hemil Gonzalez,
Igor J. Koralnik,
Gregory Huhn,
Lauren C. Tantalo,
Ethan Ritz,
Zachary S. Orban,
Christina M. Marra
Publication year - 2021
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000001308
Subject(s) - neurosyphilis , medicine , syphilis , pleocytosis , cerebrospinal fluid , confidence interval , point of care testing , receiver operating characteristic , rapid plasma reagin , csf pleocytosis , immunology , treponema , human immunodeficiency virus (hiv)
The diagnosis of neurosyphilis relies on cerebrospinal fluid (CSF) abnormalities (pleocytosis, elevated protein) and CSF-Venereal Disease Research Laboratory (VDRL) test. In resource-limited settings, the CSF-VDRL test may not be widely available.