Open AccessClinical and Personal Lubricants Impact the Growth of Vaginal Lactobacillus Species and Colonization of Vaginal Epithelial Cells: An in Vitro Study
Author(s) -
Paweł Łaniewski,
Kimberley A. Owen,
Michael Khnanisho,
Rebecca M. Brotman,
Melissa M. Herbst-Kralovetz
Publication year - 2020
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000001272
Subject(s) - lactobacillus crispatus , lactobacillus , lactobacillus gasseri , chlorhexidine , microbicide , methylparaben , microbiology and biotechnology , propylparaben , food science , lactobacillus acidophilus , medicine , probiotic , chemistry , biology , bacteria , preservative , immunology , dentistry , genetics , human immunodeficiency virus (hiv) , fermentation
Vaginal lubricants are commonly used during gynecological examinations, during sexual activities, or to alleviate vaginal dryness. Many lubricants contain potentially bacteriostatic or bactericidal agents (parabens, chlorhexidine gluconate, nonoxynol-9). Our objective was to evaluate the impact of lubricants that vary in formulation on the growth and viability of vaginal Lactobacillus species and vaginal epithelial cell (VEC) colonization in an in vitro model.