Open AccessRisk of Gonococcal Infection During Vaginal Exposure is Associated With High Vaginal pH and Active Menstruation
Author(s) -
Stephanie E. McLaughlin,
Khalil G. Ghanem,
Jonathan M. Zenilman,
J M Griffiss
Publication year - 2019
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000926
Subject(s) - medicine , gonorrhea , neisseria gonorrhoeae , menstruation , odds ratio , logistic regression , obstetrics , gynecology , menstrual cycle , sexual intercourse , population , immunology , human immunodeficiency virus (hiv) , hormone , microbiology and biotechnology , biology , environmental health
An understanding of the biological reasons why 25% to 35% of women resist infection during vaginal intercourse with a man infected with Neisseria gonorrhoeae could lead to novel control measures. We sought modifiable biological bases for infection resistance by comparing women in the same core-mixing group who did or did not become infected after sexual exposure.