Open AccessThe Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites
Author(s) -
LaoTzu AllanBlitz,
Olivia Ellis,
Robert Bolan,
Peera Hemarajata,
Romney M. Humphries,
Akbar Shahkolahi,
Mark R McGrath,
Jeffrey D. Klausner
Publication year - 2019
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000912
Subject(s) - neisseria gonorrhoeae , dna gyrase , medicine , ciprofloxacin , genotyping , genotype , gonorrhea , gonococcal infection , microbiology and biotechnology , antibiotics , virology , genetics , sexually transmitted disease , biology , syphilis , gene , escherichia coli , human immunodeficiency virus (hiv)
Gyrase A genotyping reliably predicts Neisseria gonorrhoeae susceptibility to ciprofloxacin. It is unknown whether concurrent infections at different anatomic sites harbor different susceptibility profiles. We found a 3.2% frequency of discordant gyrase A genotypes among concurrent but anatomically separate N. gonorrhoeae infections diagnosed at 2 laboratories in Los Angeles.