Open AccessUse of Oral Fluid With a Rapid Treponemal Test for Syphilis Evaluation
Author(s) -
Claire C. Bristow,
Chelsea Shan,
Sasha Herbst de Cortina,
Jeffrey D. Klausner
Publication year - 2018
Publication title -
sexually transmitted diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.507
H-Index - 105
eISSN - 1537-4521
pISSN - 0148-5717
DOI - 10.1097/olq.0000000000000840
Subject(s) - medicine , rapid plasma reagin , syphilis , titer , immunology , antibody , virology , treponema , human immunodeficiency virus (hiv)
We aimed to determine if rapid treponemal tests intended for whole-blood specimens could be used to detect treponemal antibody in oral fluid. We found a high sensitivity of oral fluid rapid testing, which increased with increasing rapid plasma reagin titer, suggesting potential for the development of accurate rapid oral syphilis tests.