Open AccessCollagen fleece in orthopaedic infections
Author(s) -
Susan Ge,
Edward J. Harvey
Publication year - 2021
Publication title -
ota international
Language(s) - Uncategorized
Resource type - Journals
ISSN - 2574-2167
DOI - 10.1097/oi9.0000000000000111
Subject(s) - adverse effect , medicine , drug delivery , intensive care medicine , biocompatible material , antibiotics , standard of care , surgery , pharmacology , biomedical engineering , biology , nanotechnology , microbiology and biotechnology , materials science
Collagen fleece is a relatively new development. It represents another option in the battle against infection. It is a cheap, biocompatible, and resorbable local antibiotic delivery mechanism with favorable drug release kinetics and low risk of adverse effects or toxicity. Benefit may be conferred when used in contaminated cases. Significantly more research is still needed before the adoption of collagen fleece as the standard of care. However, we can likely conclude that there are no major adverse effects and it can be safely used as an adjunct in addition to conventional therapies for the prophylaxis and treatment of infections.