Open AccessEvidence of Altered Corticomotor System Connectivity in Early-Stage Alzheimer's Disease
Author(s) -
Eric D. Vidoni,
George Thomas,
Robyn A. Honea,
Natalia Loskutova,
Jeffrey M. Burns
Publication year - 2012
Publication title -
journal of neurologic physical therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.046
H-Index - 52
eISSN - 1557-0584
pISSN - 1557-0576
DOI - 10.1097/npt.0b013e3182462ea6
Subject(s) - neuroscience , motor system , functional magnetic resonance imaging , coactivation , primary motor cortex , psychology , dementia , motor cortex , disease , transcranial magnetic stimulation , motor control , alzheimer's disease , supplementary motor area , physical medicine and rehabilitation , medicine , electromyography , pathology , stimulation
There is increasing evidence for subtle motor dysfunction early in Alzheimer disease (AD), including common motor behaviors that were once considered unaffected early in the disease process. Our objective was to assess whether functional neural networks underlying motor behavior are altered by AD.