Open AccessExtramedullary Infiltration in Pediatric Acute Myeloid Leukemia on Surveillance Magnetic Resonance Imaging and its Relationship With Established Risk Factors
Author(s) -
Eu Hyun Kim,
Soo Ah Im,
Jae Woo Lee,
Seongkoo Kim,
Bin Cho
Publication year - 2021
Publication title -
journal of pediatric hematology/oncology
Language(s) - English
Resource type - Journals
eISSN - 1536-3678
pISSN - 1077-4114
DOI - 10.1097/mph.0000000000002353
Subject(s) - medicine , magnetic resonance imaging , asymptomatic , radiology , bone marrow , myeloid leukemia , medical record
Extramedullary infiltration (EMI) is a rare condition defined by the accumulation of myeloid tumor cells beyond the bone marrow. The clinical significance is still controversial. This study was aimed to evaluate the incidence, characteristics, and prognostic significance of EMI on complete magnetic resonance imaging (MRI) investigation in newly diagnosed pediatric acute myeloid leukemia (AML) patients who are asymptomatic without clinical evidence to suspect EMI.