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Establishing Sickle Cell Disease Stroke Prevention Teams in Africa is Feasible: Program Evaluation Using the RE-AIM Framework
Author(s) -
Djamila Labib Ghafuri,
Shehu Umar Abdullahi,
Abdu Hamisu Dambatta,
Jamil Aliyu Galadanci,
Musa A. Tabari,
Halima BelloManga,
Nura Idris,
Hauwa Inuwa,
Aliyu Tijjani,
Aisha Suleiman,
Binta W. Jibir,
Safiya Gambo,
Awwal Gambo,
Yusuf Khalifa,
Lawal Haliru,
Sani Abdulrasheed,
Mohammed A Zakari,
Brittany Covert Greene,
Edwin Trevathan,
Lori C. Jordan,
Muktar H. Aliyu,
Ana A. Baumann,
Michael R. DeBaun
Publication year - 2021
Publication title -
journal of pediatric hematology/oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.388
H-Index - 78
eISSN - 1536-3678
pISSN - 1077-4114
DOI - 10.1097/mph.0000000000002179
Subject(s) - medicine , stroke (engine) , transcranial doppler , disease , physical therapy , sickle cell anemia , program evaluation , pathology , mechanical engineering , public administration , political science , engineering
We used the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework to evaluate a Stroke Prevention Team's readiness to prevent strokes in children with sickle cell anemia living in northern Nigeria. The NIH sponsored Stroke Prevention Trial in Nigeria included a goal of a sustainable stroke prevention program. The program's 1-year reach for transcranial Doppler screening was 14.7% (4710/32,000) of which 6.0% (281/4710) had abnormal velocities (≥200 cm/s). All participants with abnormal transcranial Doppler velocities were started on hydroxyurea (effectiveness). The leaders of all 5 hospitals agreed to adopt the program. After 1 year, program-implementation and maintenance rates were 100%, demonstrating the program's feasibility and short-term sustainability.

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