Open AccessBisphosphonate Therapy for Treating Osteonecrosis in Pediatric Leukemia Patients: A Systematic Review
Author(s) -
Shanaz M. Daneshdoost,
Jad M. El Abiad,
Kathy Ruble,
Lynne C. Jones,
Janet Crane,
Carol D. Morris,
Adam S. Levin
Publication year - 2020
Publication title -
journal of pediatric hematology/oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.388
H-Index - 78
eISSN - 1536-3678
pISSN - 1077-4114
DOI - 10.1097/mph.0000000000001793
Subject(s) - medicine , cinahl , cochrane library , meta analysis , adverse effect , bisphosphonate , systematic review , medline , bone pain , joint pain , vitamin d and neurology , osteoporosis , physical therapy , pediatrics , psychiatry , law , political science , psychological intervention
Despite improved outcomes in children with leukemia, complications such as osteonecrosis are common. We conducted a systematic review to investigate the role of bisphosphonates in reducing pain, improving mobility, and stabilizing lesions in pediatric leukemia survivors.